Bioactive compounds from local Psychotria plant species
In. Anon. Advancing Caribbean herbs in the 21st century. St. Augustine, The University of the West Indies, 2003. p.45-52, ilus.
Monography
in English
| LILACS
| ID: lil-386501
ABSTRACT
Bioassay-guided fractionation of the methanol extracts of the aerial parts of Psychotria uliginosa Sw yielded four known bioactive compounds benz[g]isoquinoline-5,10-dione and 1-hydroxy-4,7-megastigmadien-3-one and blumenol A, which are chemically related to S-(+)-dehydrovomifoliol a known inhibitor of the germination of lettuce seeds. Evaluation of the basic components obtained from the methanol extract of the aerial parts of Psychotria bahiensis DC. yielded five bioactive indole monoterpenoid alkaloids which are known to display various levels of antiplasmodial and antitumor activity 5 alpha-carboxystrictosidine, angustine, strictosamide and (E) and (Z)-vallesiachotamine; and the novel epimers bahienoside A and B which are currently being investigated for biological activity. The structures were determined by means of 1D and 2D NMR techniques
Search on Google
Index:
LILACS (Americas)
Main subject:
Plants, Medicinal
/
Trinidad and Tobago
/
Plant Extracts
Country/Region as subject:
English Caribbean
/
Trinidad and Tobago
Language:
English
Year:
2003
Type:
Congress and conference
/
Monography
Similar
MEDLINE
...
LILACS
LIS