Morphometrical and stereological analysis of the superior cervical ganglion of rattus norvegicus submitted to chronic treatment with cortisol
Int. j. morphol
;
21(3): 221-226, 2003. ilus, tab, graf
Article
in English
| LILACS
| ID: lil-388104
ABSTRACT
The present work investigates the corticoid action on the growth of the superior cervical ganglion of the rat and describes the cortisol effect during early stages of development. The study was based on morphometric and stereological analysis of the perikarya. Eight rats were treated intraperitoneally with cortisol (1mg/Kg/day) during 36 days. Treatment was initiated in the 8th day after birth and was withdrawn one day before the sacrifice. There was a significant difference (úP0,05) for the neural mean diameter between the control group (16.78 ± 1.11mm) and treated animals (15.84 ± 0.99mm). The decrease of perikarya neuronal diameter was also demonstrated by stereological methods. Morphometrical findings may suggest alterations in superior cervical ganglion neuronal activity in rats treated for long term with cortisol.
Full text:
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Index:
LILACS (Americas)
Main subject:
Hydrocortisone
/
Superior Cervical Ganglion
/
Anti-Inflammatory Agents
Limits:
Animals
Language:
English
Journal:
Int. j. morphol
Journal subject:
Anatomy
Year:
2003
Type:
Article
Affiliation country:
Brazil
Institution/Affiliation country:
Federal Fluminense University/BR
/
State of Rio de Janeiro University/BR
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