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Linfoma intravascular tratado con anticuerpos monoclonales anti CD20: descripción de un caso clínico / Intravascular lymphoma treated with anti CD20 monoclonal antibodies: report of one case
Alfaro L., Jorge; Espinoza N., Arturo; Manríquez A., María; Moyano, Leonor; González G., Néstor; Larrondo L., Milton; Figueroa M., Gastón.
  • Alfaro L., Jorge; Universidad de Chile. Hospital Clínico. Banco de SangreMedicina Interna. Laboratorio de Terapia Celular. CL
  • Espinoza N., Arturo; Clínica Dávila. Servicio de Oncología y Anatomía Patológica. Santiago. CL
  • Manríquez A., María; Clínica Dávila. Servicio de Oncología y Anatomía Patológica. Santiago. CL
  • Moyano, Leonor; Universidad de Chile. Hospital Clínico. Anatomía Patológica. CL
  • González G., Néstor; Universidad de Chile. Hospital Clínico. Sección de Hematología. CL
  • Larrondo L., Milton; Universidad de Chile. Hospital Clínico. Banco de SangreMedicina Interna. Laboratorio de Terapia Celular. CL
  • Figueroa M., Gastón; Universidad de Chile. Hospital Clínico. Sección de Medicina Interna. CL
Rev. méd. Chile ; 132(11): 1403-1406, nov. 2004. ilus
Article in Spanish | LILACS | ID: lil-391846
ABSTRACT
We report a 78 year old male with prostatism, that was subjected to a prostate biopsy. The pathological study showed a microvascular lymphocytic infiltration. Four months later, the patients presentd with reduced alertness, cough, dyspnea, fever and elevation of lactic dehydrogenase and erythrocyte sedimentation rate. Chest and abdominal CAT scans, bone marrow aspirate, protein electrophoresis and prostate specific antigen were normal. A re-evaluation of prostate biopsy showed an intravascular lymphoid infiltration, positive for CD45 and CD20, compatible with the diagnosis of intravascular lymphoma. Chemotherapy was started, but it was not tolerated by the patient and the response was partial. Therefore, treatment with monoclonal antibodies anti CD20 (Rituximab) was started. The tumor had a complete and prolonged (24 months) remission after the treatment.
Subject(s)
Full text: Available Index: LILACS (Americas) Main subject: Lymphoma, Non-Hodgkin / Vascular Neoplasms / Antibodies, Monoclonal / Antineoplastic Agents Limits: Aged / Humans / Male Language: Spanish Journal: Rev. méd. Chile Journal subject: Medicine Year: 2004 Type: Article Affiliation country: Chile Institution/Affiliation country: Clínica Dávila/CL / Universidad de Chile/CL

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Full text: Available Index: LILACS (Americas) Main subject: Lymphoma, Non-Hodgkin / Vascular Neoplasms / Antibodies, Monoclonal / Antineoplastic Agents Limits: Aged / Humans / Male Language: Spanish Journal: Rev. méd. Chile Journal subject: Medicine Year: 2004 Type: Article Affiliation country: Chile Institution/Affiliation country: Clínica Dávila/CL / Universidad de Chile/CL