The prevalence of human immunodeficiency virus type 1 and hepatitis C virus among injection drug users who use high risk inner-city locales in Miami, Florida
Mem. Inst. Oswaldo Cruz
;
99(8): 789-793, dez. 2004. tab
Article
in English
| LILACS
| ID: lil-393758
ABSTRACT
In order to estimate the prevalence of human immunodeficiency virus type 1 (HIV-1) and hepatitis C virus (HCV) co-infection in hard-to-reach intravenous drug users, 199 subjects from high-risk inner-city locales, the so called "shooting galleries", were consented, interviewed, and tested in Miami, FL, US. Positive HIV-1 status was based on repeatedly reactive ELISA and confirmatory Western Blot. Positive HCV status was based on reactive ELISA and confirmatory polymerase chain reaction techniques. Overall, 50 (25 percent) were not infected with either virus, 61 (31 percent) were HIV-1/HCV co-infected, 17 (8 percent) infected by HIV-1 only, and 71 (36 percent) infected by HCV only. The results of the multivariable analyses showed that more years using heroin was the only significant risk factor for HCV only infection (odds ratio = 1.15; 95 percent confidence interval = 1.07, 1.24) and for HIV-1/HCV co-infection (odds ratio = 1.17; 95 percent confidence interval = 1.09, 1.26). This paper demonstrates that HIV-1/HCV co-infection is highly prevalent among so called "shooting galleries".
Full text:
Available
Index:
LILACS (Americas)
Main subject:
HIV Infections
/
Substance Abuse, Intravenous
/
Hepatitis C
/
Substance-Related Disorders
Type of study:
Etiology study
/
Prevalence study
/
Risk factors
Limits:
Female
/
Humans
/
Male
Country/Region as subject:
North America
Language:
English
Journal:
Mem. Inst. Oswaldo Cruz
Journal subject:
Tropical Medicine
/
Parasitology
Year:
2004
Type:
Article
/
Project document
Affiliation country:
United States
Institution/Affiliation country:
Department of Epidemiology and Public Health/US
/
Florida Department of Health/US
/
University of Miami School of Medicine/US
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