Determinación de factores trombofílicos en pacientes con trombosis venosas retinianas / Markers of thrombophilia in patients with retinal vein thrombosis
Rev. méd. Chile
;
133(2): 167-174, feb. 2005. ilus, tab
Article
in Spanish
| LILACS
| ID: lil-398048
ABSTRACT
Background:
Thrombophilia is an alteration of hemostasis that increases the risk to venous or arterial thrombosis. This condition may be the underlying cause of retinal vein thrombosis.Aim:
To study the presence of thrombophilia in patients with retinal vein thrombosis. Patients andmethods:
Prospective study of 55 patients aged 22 to 86 years, with retinal vein thrombosis (central or branch). Antithrombin III, coagulant protein C, functional protein S, resistance to activated C protein, homocysteine, prothrombin G20210A gene, lupus anticoagulant and anticardiolipin antibodies were measured in all.Results:
Seventeen patients had thrombophilic markers (antiphospholipid syndrome in seven, hyperhomocysteinemia in six and resistance to protein C in three). Of these 17 patients, 53percent had high blood pressure, 35percent an abnormal serum lipid profile and 23percent a personal history of thrombosis. The thrombosis was central in 12 (ischemic in four) and of a branch in five (ischemic in two).Conclusions:
Thrombophilic markers must be assessed in patients with retinal vein thrombosis.
Full text:
Available
Index:
LILACS (Americas)
Main subject:
Retinal Vein Occlusion
/
Thrombophilia
Type of study:
Controlled clinical trial
/
Etiology study
/
Observational study
/
Risk factors
Limits:
Adult
/
Female
/
Humans
/
Male
Language:
Spanish
Journal:
Rev. méd. Chile
Journal subject:
Medicine
Year:
2005
Type:
Article
Affiliation country:
Chile
Institution/Affiliation country:
Fundación Oftalmológica Los Andes/CL
/
Universidad de Chile/CL
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