Prevalence of hepatitis-B surface antigen among blood donors and human immunodeficiency virus-infected patients in Jos, Nigeria
Mem. Inst. Oswaldo Cruz
;
100(1): 13-16, Feb. 2005. tab
Article
in English
| LILACS
| ID: lil-398108
ABSTRACT
Information is very scarce on the prevalence of hepatitis-B virus (HBV) infection among blood donors and patients with human immunodeficiency virus (HIV) infection in Nigeria. Hepatitis-B surface antigen (HBsAg) ELISA was used to determined the prevalence of HBsAg among 175 blood donors (aged 20-40 years) and 490 HIV-infected patients (aged 17-60 years) in Jos, Nigeria. Twenty-five (14.3 percent) of the blood donors and 127 (25.9 percent) of the HIV-infected individuals were HBsAg seropositive, indicating a higher HBV infection among HIV-infected persons than among healthy blood donors. A slightly higher HBsAg seroprevalence was recorded in the males (14.6 percent) than females (12.9 percent) of the blood donors. Among the HIV-infected patients, the males had considerably higher HBsAg seroprevalence than the females (31.8 vs 22.1 percent) with the highest prevalence of HBsAg occurring in the 51-60 years age group (44 percent), followed by those of 31-40 years (28.2 percent). Results confirmed the high endemicity of HBV infection in Jos, Nigeria and the significantly greater prevalence of HBV infection among HIV -infected patients than among blood donors.
Full text:
Available
Index:
LILACS (Americas)
Main subject:
Blood Donors
/
HIV Infections
/
Hepatitis B virus
/
Hepatitis B
/
Hepatitis B Surface Antigens
Type of study:
Diagnostic study
/
Prevalence study
/
Risk factors
Limits:
Adolescent
/
Adult
/
Female
/
Humans
/
Male
Country/Region as subject:
Africa
Language:
English
Journal:
Mem. Inst. Oswaldo Cruz
Journal subject:
Tropical Medicine
/
Parasitology
Year:
2005
Type:
Article
Affiliation country:
Nigeria
Institution/Affiliation country:
Ebonyi State University/NG
/
GEDE AIDS & Infectious Diseases Research Institute/NG
/
Jos University Teaching Hospital/NG
/
University of Jos/NG
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