Severe refractory sarcoidosis in a 64-year-old man with persistent leucopenia
West Indian med. j
;
52(1): 56-58, Mar. 2003.
Article
in English
| LILACS
| ID: lil-410829
ABSTRACT
We present a case of bone marrow granulomas in a 64-year-old West Indian man who presented with severe leucopenia, anaemia, thrombocytopenia, hepatosplenomegaly, hypercalcaemia, hypercalciuria, elevated angiotensin converting enzyme level and reticulo-nodular shadows on chest X-ray. Bone marrow biopsy revealed numerous non-caseating epithelioid granulomas. A diagnosis of sarcoidosis was made and he was treated with prednisolone 60 mg daily for four weeks and the dose was subsequently reduced to 30 mg daily. Eight months follow-up revealed persistent pancytopenia. Bone marrow granulomas are rare and, when they occur, sarcoidosis is an uncommon aetiology. This case illustrates that severe leucopenia may occur in sarcoidosis and may present therapeutic difficulties
Search on Google
Index:
LILACS (Americas)
Main subject:
Sarcoidosis
/
Bone Marrow Diseases
/
Leukopenia
Type of study:
Diagnostic study
Limits:
Humans
/
Male
Language:
English
Journal:
West Indian med. j
Journal subject:
Medicine
Year:
2003
Type:
Article
Affiliation country:
United States
Similar
MEDLINE
...
LILACS
LIS