Genetic characterization of Trypanosoma cruzi natural clones from the state of Paraíba, Brazil
Mem. Inst. Oswaldo Cruz
;
100(3): 273-275, May 2005. tab
Article
in English
| LILACS
| ID: lil-411023
ABSTRACT
Eighteen Trypanosoma cruzi stocks from the state of Paraíba, Brazil, isolated from man, wild mammals, and triatomine bugs were studied by multilocus enzyme electrophoresis and random primed amplified polymorphic DNA. Despite the low number of stocks, a notable genetic, genotypic, and phylogenetic diversity was recorded. The presence of the two main phylogenetic subdivisions, T. cruzi I and II, was recorded. The strong linkage disequilibrium observed in the population under survey suggests that T. cruzi undergoes predominant clonal evolution in this area too, although this result should be confirmed by a broader sample. The pattern of clonal variation does not suggests a recent origin by founder effect with a limited number of different genotypes.
Full text:
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Index:
LILACS (Americas)
Main subject:
Trypanosoma cruzi
/
Genetic Variation
/
DNA, Protozoan
Limits:
Animals
/
Humans
Country/Region as subject:
South America
/
Brazil
Language:
English
Journal:
Mem. Inst. Oswaldo Cruz
Journal subject:
Tropical Medicine
/
Parasitology
Year:
2005
Type:
Article
/
Project document
Affiliation country:
Brazil
/
France
Institution/Affiliation country:
Institut de Recherche pour le Développement/FR
/
Universidade Federal de Santa Catarina/BR
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