Intraoperative application of topical mitomycin C 0.05 for pterygium surgery
Bol. Asoc. Méd. P. R
;
96(2): 100-102, Mar.-Apr. 2004.
Article
in English
| LILACS
| ID: lil-411067
ABSTRACT
BACKGROUND:
Pterygium recurrence is a common problem encountered by ophthalmic surgeons. Several methods have been suggested to avoid these recurrences. We studied the recurrence rate of pterygium after administration of a single intraoperative dosage of topical mitomycin C 0.05.METHODS:
A retrospective analysis of fifty eyes in forty-nine patients who underwent pterygium excision by the same surgeon using intraoperative topical mitomycin C during the years 2002--2003. Mitomycin concentration was 0.05 applied to pterygium and adjacent areas after undermining and separation from sclera but prior to excision for three minutes. Postoperative follow up time was 12 months.RESULTS:
The pterygium recurred in 4 (8) eyes. Another four eyes (8) had a cosmetically acceptable recurrence of < 2.0 mm. The only complication was a corneal dellen in one eye.CONCLUSION:
Intraoperative administration of mitomycin C at 0.05 is safe and effective in preventing pterygium recurrences
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Index:
LILACS (Americas)
Main subject:
Pterygium
/
Mitomycin
/
Alkylating Agents
Type of study:
Observational study
/
Risk factors
Limits:
Adult
/
Female
/
Humans
/
Male
Language:
English
Journal:
Bol. Asoc. Méd. P. R
Journal subject:
Medicine
Year:
2004
Type:
Article
Affiliation country:
Puerto Rico
Institution/Affiliation country:
University of Puerto Rico School of Medicine/PR
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