T-cell rich B-cell lymphoma masquerading as Hodgkin disease: excellent outcome to inadequate therapy
Bol. Asoc. Méd. P. R
;
88(4/6): 32-34, Apr.-Jun. 1996.
Article
in English
| LILACS
| ID: lil-411533
RESUMO
T-cell rich B-cell lymphomas (TCRBCL) are characterized as non-Hodgkin lymphomas with a minor population of malignant B-cells scattered among predominant, reactive T-lymphocytes. This entity can easily be confused with lymphocyte-predominant Hodgkin disease (HD-LP), resulting in inappropriate therapy and a poor outcome. Because of their similarity, the pathology of patients treated for HD-LP with an inadequate or short-lived response to therapy should always be reviewed by an expert hematopathologist. We describe the first reported patient in Puerto Rico with TCRBCL, originally diagnosed and treated as HD-LP. Although the patient received partial, substandard therapy for TCRBCL, an excellent prolonged complete response ensued, thus, giving further credence to the fact that malignant lymphomas and TCRBCL in particular, are a protean group of disorders which should be precisely and accurately classified before the proper therapeutic strategies can be outlined
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Index:
LILACS (Americas)
Main subject:
Hodgkin Disease
/
Lymphoma, B-Cell
Type of study:
Diagnostic study
Limits:
Adult
/
Humans
/
Male
Language:
English
Journal:
Bol. Asoc. Méd. P. R
Journal subject:
Medicine
Year:
1996
Type:
Article
Affiliation country:
Puerto Rico
Institution/Affiliation country:
University of Puerto Rico/PR
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