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p-53: Applications in internal medicine and predictive significance
Geller, Mauro; Ribeiro, Marcia G; Araujo, Alexandra Prufer de Q. C.
  • Geller, Mauro; Universidade Federal do Rio de Janeiro. Rio de Janeiro. BR
  • Ribeiro, Marcia G; Universidade Federal do Rio de Janeiro. Rio de Janeiro. BR
  • Araujo, Alexandra Prufer de Q. C; Universidade Federal do Rio de Janeiro. Rio de Janeiro. BR
RBM rev. bras. med ; 62(1/2): 17-22, jan.-fev. 2005.
Article in English | LILACS | ID: lil-414756
RESUMO
The authors present a review of the properties and functions of the p53 gene and its protein product, along with clinical correlations for tumor development. The genetic expression and prognostic evaluation as well as therapies is reviewed. Also discussed is the importance of mutations in the p53 gene and its protein product in various neoplasias is reviewed.(au)
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Index: LILACS (Americas) Main subject: Chromosomes, Human, Pair 17 / Genes, p53 / Tumor Suppressor Protein p53 / Neoplasms Type of study: Prognostic study / Risk factors Limits: Humans Language: English Journal: RBM rev. bras. med Journal subject: Medicine Year: 2005 Type: Article Affiliation country: Brazil Institution/Affiliation country: Universidade Federal do Rio de Janeiro/BR

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Index: LILACS (Americas) Main subject: Chromosomes, Human, Pair 17 / Genes, p53 / Tumor Suppressor Protein p53 / Neoplasms Type of study: Prognostic study / Risk factors Limits: Humans Language: English Journal: RBM rev. bras. med Journal subject: Medicine Year: 2005 Type: Article Affiliation country: Brazil Institution/Affiliation country: Universidade Federal do Rio de Janeiro/BR