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Escherichia coli as a model system to study DNA repair genes of eukaryotic organisms
Augusto-Pinto, L; Silva, C. G. da; Lopes, D. de O; Machado-Silva, A; Machado, C. R.
  • Augusto-Pinto, L; Universidade Federal de Minas Gerais. Departamento de Bioquímica e Imunologia. Belo Horizonte. BR
  • Silva, C. G. da; Universidade Federal de Minas Gerais. Departamento de Bioquímica e Imunologia. Belo Horizonte. BR
  • Lopes, D. de O; Universidade Federal de Minas Gerais. Departamento de Bioquímica e Imunologia. Belo Horizonte. BR
  • Machado-Silva, A; Universidade Federal de Minas Gerais. Departamento de Bioquímica e Imunologia. Belo Horizonte. BR
  • Machado, C. R; Universidade Federal de Minas Gerais. Departamento de Bioquímica e Imunologia. Belo Horizonte. BR
Genet. mol. res. (Online) ; 2(1): 77-91, Mar. 2003.
Article in English | LILACS | ID: lil-417622
RESUMO
The bacteria Escherichia coli has been widely employed in studies of eukaryotic DNA repair genes. Several eukaryotic genes have been cloned by functional complementation of mutant lineages of E. coli. We examined the similarities and differences among bacterial and eukaryotic DNA repair systems. Based on these data, we examined tools used for gene cloning and functional studies of DNA repair in eukaryotes, using this bacterial system as a model
Subject(s)
Full text: Available Index: LILACS (Americas) Main subject: DNA Repair / Escherichia coli / Eukaryotic Cells Limits: Animals Language: English Journal: Genet. mol. res. (Online) Journal subject: Molecular Biology / Genetics Year: 2003 Type: Article Affiliation country: Brazil Institution/Affiliation country: Universidade Federal de Minas Gerais/BR

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Full text: Available Index: LILACS (Americas) Main subject: DNA Repair / Escherichia coli / Eukaryotic Cells Limits: Animals Language: English Journal: Genet. mol. res. (Online) Journal subject: Molecular Biology / Genetics Year: 2003 Type: Article Affiliation country: Brazil Institution/Affiliation country: Universidade Federal de Minas Gerais/BR