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Prediction of pathological stage in prostate cancer through the percentage of involved fragments upon biopsy
Dall'oglio, Marcos F; Crippa, Alexandre; Oliveira, Luis C; Neves Neto, Joao F; Leite, Katia R; Srougi, Miguel.
  • Dall'oglio, Marcos F; Federal University of Sao Paulo. Paulista School of Medicine. Division of Urology. Sao Paulo. BR
  • Crippa, Alexandre; Federal University of Sao Paulo. Paulista School of Medicine. Division of Urology. Sao Paulo. BR
  • Oliveira, Luis C; Federal University of Sao Paulo. Paulista School of Medicine. Division of Urology. Sao Paulo. BR
  • Neves Neto, Joao F; Federal University of Sao Paulo. Paulista School of Medicine. Division of Urology. Sao Paulo. BR
  • Leite, Katia R; Federal University of Sao Paulo. Paulista School of Medicine. Division of Urology. Sao Paulo. BR
  • Srougi, Miguel; Federal University of Sao Paulo. Paulista School of Medicine. Division of Urology. Sao Paulo. BR
Int. braz. j. urol ; 31(5): 445-451, Sept.-Oct. 2005. tab, graf
Article in English | LILACS | ID: lil-418163
RESUMO

INTRODUCTION:

The need for defining the extension of disease in patients undergoing radical prostatectomy due to prostate adenocarcinoma is a relevant factor cure in such individuals. In order to identify a new independent preoperative factor for predicting the extension of prostate cancer, we assessed the role of the percentage of positive fragments upon biopsy. MATERIALS AND

METHODS:

A retrospective study compared the percentage of positive fragments on biopsy with the extension of disease as defined by the pathological examination of the surgical specimen from 898 patients undergoing radical prostatectomy due to clinically localized prostate cancer.

RESULTS:

On the univariate analysis, the percentage of positive fragments on biopsy showed a statistical significance for predicting confined disease (p < 0.001), which was found in 66.7 percent of the cases under study. Additionally, we observed that the total number of removed fragments exerts no influence on the extension of the disease (p = 0.567).

CONCLUSION:

the percentage of positive fragments is an independent factor for predicting the pathological stage of prostate adenocarcinoma, and the number of removed fragments is not related to the extension of the disease.
Subject(s)
Full text: Available Index: LILACS (Americas) Main subject: Prostate / Prostatic Neoplasms / Adenocarcinoma Type of study: Observational study / Prognostic study / Risk factors Limits: Adult / Aged / Aged80 / Humans / Male Language: English Journal: Int. braz. j. urol Journal subject: Urology Year: 2005 Type: Article Affiliation country: Brazil Institution/Affiliation country: Federal University of Sao Paulo/BR

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Full text: Available Index: LILACS (Americas) Main subject: Prostate / Prostatic Neoplasms / Adenocarcinoma Type of study: Observational study / Prognostic study / Risk factors Limits: Adult / Aged / Aged80 / Humans / Male Language: English Journal: Int. braz. j. urol Journal subject: Urology Year: 2005 Type: Article Affiliation country: Brazil Institution/Affiliation country: Federal University of Sao Paulo/BR