Cutaneous periumbilical purpura in disseminated strongyloidiasis in cancer patients: a pathognomonic feature of potentially lethal disease?
Braz. j. infect. dis
;
9(5): 419-424, Oct. 2005. ilus, tab
Article
in English
| LILACS
| ID: lil-419652
ABSTRACT
Cutaneous manifestations in disseminated strongyloidiasis are infrequent but should raise the suspicion for its diagnosis. We retrospectively evaluated the charts of six patients with cancer and a proven diagnosis of disseminated strongyloidiasis. All patients had received prophylaxis with albendazole before starting antineoplastic therapy, which included high-dose steroids. They presented with septic shock, acute respiratory failure and characteristic purpuric periumbilical skin lesions. Strongyloides larvae were identified in tracheal aspirates (n=5), gastric aspirates (n=4), lung (n=2) and skin biopsies (n=2). All patients died despite antihelminthic therapy and intensive care support.
Full text:
Available
Index:
LILACS (Americas)
Main subject:
Purpura
/
Skin Diseases, Parasitic
/
Strongyloidiasis
/
Strongyloides stercoralis
/
Neoplasms
Type of study:
Prognostic study
Limits:
Animals
/
Female
/
Humans
/
Male
Language:
English
Journal:
Braz. j. infect. dis
Journal subject:
Communicable Diseases
Year:
2005
Type:
Article
Affiliation country:
Brazil
/
United States
Institution/Affiliation country:
Federal University of Rio de Janeiro/BR
/
Harvard Medical School/US
/
National Institute of Cancer/BR
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