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Serologic evidence of human metapneumovirus circulation in Uruguay
Mirazo, Santiago; Ruchansky, Dora; Blanc, Andrea; Arbiza, Juan.
  • Mirazo, Santiago; Universidad de la República. Facultad de Ciencias. Sección Virología. Montevideo. UY
  • Ruchansky, Dora; Universidad de la República. Facultad de Ciencias. Sección Virología. Montevideo. UY
  • Blanc, Andrea; Universidad de la República. Facultad de Ciencias. Sección Virología. Montevideo. UY
  • Arbiza, Juan; Universidad de la República. Facultad de Ciencias. Sección Virología. Montevideo. UY
Mem. Inst. Oswaldo Cruz ; 100(7): 715-718, Nov. 2005. tab, graf
Article in English | LILACS | ID: lil-419693
ABSTRACT
First identified in 2001, the human metapneumovirus (hMPV), is a respiratory tract pathogen that affects young children, elderly, and immunocompromised patients. The present work represents the first serologic study carried out in Uruguay. It was performed with the purpose of obtaining serological evidence of hMPV circulation in Uruguay and to contribute to the few serologic reports described until now. Sixty nine serum samples collected between 1998 and 2001 by vein puncture from patients without respiratory symptoms or underlying pathology aged 6 days to 60 years were examined using an indirect immunofluorescence assay (IFA). The global seropositivity rate of the samples was 80 percent (55/69). Rates of 60 percent (15/25) and 91 percent (40/44) were observed for the pediatric and adult cohorts, respectively. Results obtained from a longitudinal analysis of 6 children aged 6 days to 18 months are discussed. These results are a clear evidence of hMPV circulation in Uruguay, at least since 1998, and reinforce the previous data on worldwide circulation of this virus.
Subject(s)
Full text: Available Index: LILACS (Americas) Main subject: Paramyxoviridae Infections / Metapneumovirus / Antibodies, Viral Type of study: Observational study / Prevalence study / Risk factors Limits: Adolescent / Adult / Humans / Infant / Infant, Newborn Country/Region as subject: South America / Uruguay Language: English Journal: Mem. Inst. Oswaldo Cruz Journal subject: Tropical Medicine / Parasitology Year: 2005 Type: Article Affiliation country: Uruguay Institution/Affiliation country: Universidad de la República/UY

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Full text: Available Index: LILACS (Americas) Main subject: Paramyxoviridae Infections / Metapneumovirus / Antibodies, Viral Type of study: Observational study / Prevalence study / Risk factors Limits: Adolescent / Adult / Humans / Infant / Infant, Newborn Country/Region as subject: South America / Uruguay Language: English Journal: Mem. Inst. Oswaldo Cruz Journal subject: Tropical Medicine / Parasitology Year: 2005 Type: Article Affiliation country: Uruguay Institution/Affiliation country: Universidad de la República/UY