Síndrome neuroléptico maligno y poliserositis en paciente usuaria de clozapina: una asociación infrecuente / Malignant neuroleptic syndrome and polyserositis associated to clozapine use: report of one case
Rev. méd. Chile
;
133(10): 1225-1228, oct. 2005.
Article
in Spanish
| LILACS
| ID: lil-420139
ABSTRACT
Malignant neuroleptic syndrome is a complication of antipsychotic medication use. Clozapine use is also associated with polyserositis and eosinophilia. We report a 17 years old female treated with clozapine, valproic acid, lithium carbonate and lorazepam that consulted in the emergency room for confusion, lethargy, catatonia, rigidity, myalgya and fever. Complete blood count showed eosinophilia. An abdominal CAT scan showed ascites and pleural effusion. Clozapine was discontinued and bromocriptine was started. One week after admission, the patient remained febrile and liver enzymes were elevated. Valproic acid was discontinued. Inflammatory parameters stated to subside and the patient was discharged afebrile days after admission.
Full text:
Available
Index:
LILACS (Americas)
Main subject:
Antipsychotic Agents
/
Clozapine
/
Neuroleptic Malignant Syndrome
Type of study:
Risk factors
Limits:
Adolescent
/
Female
/
Humans
Language:
Spanish
Journal:
Rev. méd. Chile
Journal subject:
Medicine
Year:
2005
Type:
Article
Affiliation country:
Chile
Institution/Affiliation country:
Pontificia Universidad Católica de Chile/CL
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