Função endotelial em adultos jovens com infarto do miocárdio: influências ambientais e genéticas / Endothelium function in young adults with myocardial infarction: environomental and genetic influences
São Paulo; s.n; 2005. [160] p. ilus, tab, graf.
Thesis
in Portuguese
| LILACS, SES-SP
| ID: lil-424888
RESUMO
A disfunção endotelial atua tanto na aterogênese como na precipitação das síndromes coronárias agudas. A redução da biodisponibilidade do óxido nítrico é expressão de endotélio disfuncional. O mecanismo desta redução não está elucidado. A presença de disfunção endotelial foi correlacionada com fatores de risco (FR), nitrato sanguíneo e fatores genéticos (polimorfismo do óxido nítrico sintase endotelial / The endothelial dysfunction plays an important roll in the atherogenesis and precipitation of acute coronary syndromes. The reduction of bioavailability of the nitric oxide is the expression of endothelial dysfunction. The exact mechanism of this reduction is not yet well explained. In order to evaluate the presence of endothelial dysfunction and correlation with risk factors (FR), nitrate blood levels and genetic factors (endothelial nitric oxide syntethase polymorphism, fibrinogen and PAI-1) a 128 myocardial infarction patients group with age ≤ 40 year was studied, and underwent a brachial artery ultra-sound. The results were compared with a group of young health individuals...
Full text:
Available
Index:
LILACS (Americas)
Main subject:
Vasodilation
/
Endothelium-Dependent Relaxing Factors
/
Endothelium
Type of study:
Risk factors
Limits:
Adult
Language:
Portuguese
Year:
2005
Type:
Thesis
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