Síndrome miasteniforme de Lambert-Eaton idiopático: Report of one case / Idiopathic Lambert-Eaton myasthenic syndrome
Rev. méd. Chile
;
134(2): 217-223, feb. 2006. tab, graf
Article
in Spanish
| LILACS
| ID: lil-425972
ABSTRACT
Lambert-Eaton myasthenic syndrome (LEMS) is an autoinmune idiopathic or paraneoplastic syndrome producing antibodies agaisnt presynaptic voltage calcium channels. The clinical features of patients with LEMS are muscle weakness and autonomic dysfunction. We report a 40 years old man with a four years history of proximal weakness, absent tendon reflexes and dry mouth. The diagnosis was confirmed by characteristic electromyographic findings, showing a low-amplitude muscle response that increased dramatically after activation. Circulating antibodies to voltage-gated calcium channel were present. The search for malignant tumors was negative. The patient was treated with prednisone and azathioprine and after four months, he was able to walk and signs of autonomic dysfunction started to subside.
Full text:
Available
Index:
LILACS (Americas)
Main subject:
Lambert-Eaton Myasthenic Syndrome
Limits:
Adult
/
Humans
/
Male
Language:
Spanish
Journal:
Rev. méd. Chile
Journal subject:
Medicine
Year:
2006
Type:
Article
Affiliation country:
Chile
Institution/Affiliation country:
Centro de Referencia de Salud Dr/CL
/
Centro de Referencia de Salud Dr. Salvador Allende Gossens/CL
/
Universidad Católica de Chile/CL
/
Universidad de Chile/CL
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