Hierro, oxígeno y desarrollo placentario en la génesis de la preeclampsia: Efectos de la altura en Ecuador / Iron, oxygen and placental development in the etiology of preeclampsia: Effects of high altitude in Ecuador
Rev. méd. Chile
;
134(4): 491-498, abr. 2006. tab
Article
in Spanish
| LILACS
| ID: lil-428551
ABSTRACT
Preeclampsia is the second cause of maternal death in Ecuador. The etiology of this condition is probably a placental alteration, although the details are not well known. The development of the placenta is closely related to the availability of oxygen. A defect in the differentiation of trophoblastic cells due to a faulty sensitization to changes in oxygen pressure, could be the cause of the alteration in placental development. The role of iron and local environmental conditions of a susceptible population, should be considered in the study of the etiology of preeclampsia. In the Andrean area of Ecuador, the high incidence of preeclampsia could be explained by the high prevalence of anemia and high altitude. However more studies are required to establish a close link between the environmental conditions of this area and the imperfect placental development.
Full text:
Available
Index:
LILACS (Americas)
Main subject:
Oxygen
/
Placentation
/
Pre-Eclampsia
/
Anemia, Iron-Deficiency
/
Altitude
/
Iron
Type of study:
Etiology study
/
Risk factors
Limits:
Female
/
Humans
/
Pregnancy
Country/Region as subject:
South America
/
Ecuador
Language:
Spanish
Journal:
Rev. méd. Chile
Journal subject:
Medicine
Year:
2006
Type:
Article
Affiliation country:
Chile
/
Ecuador
Institution/Affiliation country:
Pontificia Universidad Católica de Chile/CL
/
Universidad Central del Ecuador/EC
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