Profound peripheral T-lymphocyte depletion and activation in disseminated tuberculosis
Braz. j. infect. dis
;
10(1): 59-61, Feb. 2006. tab
Article
in English
| LILACS
| ID: lil-428718
ABSTRACT
Three HIV-1-seronegative patients with disseminated tuberculosis presented significant depletion of T-cell counts, in CD4+ and/or CD8+ cells, associated with increased expression of activation marker CD38 on CD8+ T-lymphocytes. This finding raises the question of potential mechanisms involved in the activation or loss of T-cells in disseminated tuberculosis.
Full text:
Available
Index:
LILACS (Americas)
Main subject:
Tuberculosis, Pulmonary
/
Lymphocyte Activation
/
T-Lymphocytes
/
Mycobacterium tuberculosis
Type of study:
Diagnostic study
/
Observational study
/
Risk factors
Limits:
Adult
/
Female
/
Humans
/
Male
Language:
English
Journal:
Braz. j. infect. dis
Journal subject:
Communicable Diseases
Year:
2006
Type:
Article
Affiliation country:
Brazil
Institution/Affiliation country:
Federal University of São Paulo/BR
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