Seroepidemiological study of herpes simplex virus type 2 in patients with the acquired immunodeficiency syndrome in the city of Niterói, Rio de Janeiro, Brazil
Mem. Inst. Oswaldo Cruz
;
101(3): 315-319, May 2006. tab
Article
in English
| LILACS
| ID: lil-431732
RESUMO
This study was designed to determine the seroprevalence of herpes simplex virus type 2 (HSV-2) and to evaluate its association with age, sex as well as other demographic and behavioural factors in 150 human immunodeficiency virus (HIV) positive adults patients attending the general medical outpatient ward for routine care of Niterói, state of Rio de Janeiro, Brazil. Serum samples were screened for HSV-2 antibodies using an indirect ELISA. Eighty-three patients were men (mean age 38.8) and 67 were women (mean age 35.4). The estimated prevalence of HSV-2 was 52 percent (95 percent CI 44-60 percent) and it was higher among men (53 percent) than among women (50.7 percent). Overall, the age of first sexual intercourse and past history of genital herpes were associated with HSV-2 seropositivity. Analysis by gender disclosed significant association of number of lifetime sex partners only among men. Although HSV-2 antibodies were frequent in the study group, genital herpes was reported by 21.8 percent of the HSV-2 positive subjects, indicating low awareness of the HSV-2 infection. These results may have public health importance for Brazil as the high rate of HSV-2 infection may act as a cofactor of HIV transmission.
Full text:
Available
Index:
LILACS (Americas)
Main subject:
Immunoglobulin G
/
Herpes Genitalis
/
HIV Infections
/
Herpesvirus 2, Human
/
Antibodies, Viral
Type of study:
Diagnostic study
/
Etiology study
/
Prevalence study
/
Risk factors
Limits:
Adult
/
Female
/
Humans
/
Male
Country/Region as subject:
South America
/
Brazil
Language:
English
Journal:
Mem. Inst. Oswaldo Cruz
Journal subject:
Tropical Medicine
/
Parasitology
Year:
2006
Type:
Article
Affiliation country:
Brazil
Institution/Affiliation country:
Fundação Municipal de Saúde/BR
/
Fundação Oswaldo Cruz/BR
/
Hospital Universitário Antonio Pedro/BR
/
Universidade Federal Fluminense/BR
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