Virulence attenuation and phenotypic variation of Paracoccidioides brasiliensis isolates obtained from armadillos and patients
Mem. Inst. Oswaldo Cruz
;
101(3): 331-334, May 2006.
Article
in English
| LILACS
| ID: lil-431735
RESUMO
Paracoccidioides brasiliensis is the etiological agent of paracoccidioidomycosis, the most important systemic mycosis in Latin America. The virulence profiles of five isolates of P. brasiliensis were studied in two different moments and correlated with some colonial phenotypic aspects. We observed a significant decrease in the virulence and an intense phenotypic variation in the mycelial colony. The recognition of all ranges of phenotypic and virulence variation of P. brasiliensis, as well as its physiological and genetic basis, will be important for a better comprehension of its pathogenic and epidemiological features.
Full text:
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Index:
LILACS (Americas)
Main subject:
Paracoccidioides
/
Paracoccidioidomycosis
/
Phenotype
Type of study:
Prognostic study
Limits:
Animals
/
Humans
/
Male
Country/Region as subject:
South America
/
Brazil
Language:
English
Journal:
Mem. Inst. Oswaldo Cruz
Journal subject:
Tropical Medicine
/
Parasitology
Year:
2006
Type:
Article
Affiliation country:
Brazil
Institution/Affiliation country:
1Universidade Estadual Paulista/BR
/
Universidade Estadual Paulista/BR
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