Antioxidant activity of extract from Polygonum aviculare L
Biol. Res
;
39(2): 281-288, 2006. ilus, tab
Article
in English
| LILACS
| ID: lil-432430
ABSTRACT
Free radicals induce numerous diseases by lipid peroxidation, protein peroxidation, and DNA damage. It has been reported that numerous plant extracts have antioxidant activities to scavenge free radicals. Whether Polygonum aviculare L. (Polygonaceae) has antioxidant activity is unknown. In this study, dried Polygonum aviculare L. was extracted by ethanol, and the extract was lyophilized. The antioxidant activities of extract powder were examined by free radical scavenging assays, superoxide radical scavenging assays, lipid peroxidation assays and hydroxyl radical-induced DNA strand scission assays. The results show that the IC50 value of Polygonum aviculare L. extract is 50 µg/ml in free radical scavenging assays, 0.8 µg/ml in superoxide radical scavenging assays, and 15 µg/ml in lipid peroxidation assays, respectively. Furthermore, Polygonum aviculare L. extract has DNA protective effect in hydroxyl radical-induced DNA strand scission assays. The total phenolics and flavonoid content of extract is 677.4 ± 62.7 µg/g and 112.7 ± 13 µg/g. The results indicate that Polygonum aviculare L. extract clearly has antioxidant effects.
Full text:
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Index:
LILACS (Americas)
Main subject:
DNA Damage
/
Lipid Peroxidation
/
Free Radical Scavengers
/
Polygonum
/
Antioxidants
Limits:
Animals
Language:
English
Journal:
Biol. Res
Journal subject:
Biology
Year:
2006
Type:
Article
/
Project document
Affiliation country:
China
Institution/Affiliation country:
Chang Gung University/CN
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