Osteonecrosis en lupus eritematoso sistémico / Osteonecrosis in systemic lupus erythematosus
Rev. chil. reumatol
;
21(2): 79-83, 2005. tab
Article
in Spanish
| LILACS
| ID: lil-432951
RESUMO
Osteonecrosis (ON) is a clinical entity characterized by aseptic necrosis of bone marrow and trabecular bone as a result of significant disruption of blood supply to the bone. In patients with systemic lupus erythematosus (SLE), ON is a well recognized complication, which also results in significant morbidity. The clinical course is usually progressive to end stage degenerative changes of the joints causing significant secondary pain and limitation of movement, and reducing the quality of life in these patients. Corticosteriod therapy is the major predisposing factor for ON in SLE. This article reviews the causes, clinical and epidemiological features, diagnosis and treatment options for ON among patients with SLE.
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Index:
LILACS (Americas)
Main subject:
Osteonecrosis
/
Lupus Erythematosus, Systemic
Type of study:
Etiology study
/
Risk factors
Limits:
Humans
Language:
Spanish
Journal:
Rev. chil. reumatol
Journal subject:
Rheumatology
Year:
2005
Type:
Article
Affiliation country:
Chile
Institution/Affiliation country:
Pontificia Universidad Católica de Chile/CL
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