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Asymptomatic primary hyperparathyroidism / Hiperparatiroidismo primário assintomático
Bilezikian, John P; Rubin, Mishaela; Silverberg, Shonni J.
Affiliation
  • Bilezikian, John P; Columbia University. College of Physicians & Surgeons. Department of Medicine. Division of Endocrinology. New York. US
  • Rubin, Mishaela; Columbia University. College of Physicians & Surgeons. Department of Medicine. Division of Endocrinology. New York. US
  • Silverberg, Shonni J; Columbia University. College of Physicians & Surgeons. Department of Medicine. Division of Endocrinology. New York. US
Arq. bras. endocrinol. metab ; 50(4): 647-656, ago. 2006. ilus, graf, tab
Article in En, Pt | LILACS | ID: lil-437615
Responsible library: BR1.1
ABSTRACT
Primary hyperparathyroidism is a common disorder of mineral metabolism characterized by incompletely regulated, excessive secretion of parathyroid hormone from one or more of the parathyroid glands. In adults with the disease, a single, benign adenoma is seen approximately 80 percent of the time, with multiple gland involvement comprising most of the remaining patients. Very rarely, a parathyroid cancer is responsible but it is seen in less than 0.5 percent of patients with primary hyperparathyroidism. In this article, we will review important clinical and diagnostic features of asymptomatic primary hyperparathyroidism as well as considerations for surgical or medical management of the disease.
RESUMO
O hiperparatiroidismo primário é uma distúrbio comum do metabolismo mineral, caracterizado por um excesso de secreção do hormônio das paratiróides, de uma ou mais glândulas paratiroidianas. Nos pacientes adultos portadores da doença, um adenoma único é responsável por aproximadamente 80 por cento dos casos, e o envolvimento de múltiplas glândulas pelo restante dos casos. Muito raramente um câncer de paratiróide é a causa, sendo visto em menos de 0,5 por cento dos pacientes com hiperparatiroidismo. Neste artigo, revisaremos as características clínicas e diagnósticas do hiperparatiroidismo primário assintomático, bem como o tratamento clínico e cirúrgico.
Subject(s)
Full text: 1 Index: LILACS Main subject: Hyperparathyroidism, Primary Limits: Humans Language: En / Pt Journal: Arq. bras. endocrinol. metab Journal subject: ENDOCRINOLOGIA / METABOLISMO Year: 2006 Type: Article / Project document
Full text: 1 Index: LILACS Main subject: Hyperparathyroidism, Primary Limits: Humans Language: En / Pt Journal: Arq. bras. endocrinol. metab Journal subject: ENDOCRINOLOGIA / METABOLISMO Year: 2006 Type: Article / Project document