Primary resistance of human immunodeficiency virus type 1 in a reference center in Recife, Pernambuco, Brazil
Mem. Inst. Oswaldo Cruz
;
101(8): 845-849, Dec. 2006. tab
Article
in English
| LILACS
| ID: lil-440570
ABSTRACT
To assess the prevalence of primary resistance of human immunodeficiency virus type 1 (HIV-1) to antiretrovirals, 84 patients chronically infected with HIV without prior antiretroviral treatment from Northeast Brazil were studied. Genotyping was performed using the ViroSeqTM Genotyping System. Thimidine analog mutations occurred in 3 (3.6 percent) patients. Accessory mutations related to NRTI occurred in 6 (7.1 percent) and related to PI in 67 (79.8 percent). Subtypes B (72.6 percent), F (22.6 percent), B/F 3 (3.6 percent), and C (1.2 percent) were detected. A low prevalence of major mutations related to NRTI in patients chronically infected by HIV was observed.
Full text:
Available
Index:
LILACS (Americas)
Main subject:
HIV Infections
/
HIV-1
/
Anti-HIV Agents
/
Drug Resistance, Viral
Type of study:
Prevalence study
/
Risk factors
Limits:
Adolescent
/
Adult
/
Female
/
Humans
/
Male
Country/Region as subject:
South America
/
Brazil
Language:
English
Journal:
Mem. Inst. Oswaldo Cruz
Journal subject:
Tropical Medicine
/
Parasitology
Year:
2006
Type:
Article
Affiliation country:
Brazil
Institution/Affiliation country:
Hospital das Clinicas/BR
/
Secretaria Estadual de Saude de Pernambuco/BR
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