Prevalence of hepatitis A virus infection in Afro-Brazilian isolated communities in Central Brazil
Mem. Inst. Oswaldo Cruz
;
102(1): 121-123, Feb. 2007. tab
Article
in English
| LILACS
| ID: lil-440640
ABSTRACT
To investigate hepatitis A virus (HAV) infection rates among isolated African-descendant communities in Central Brazil, 947 subjects were interviewed about demographic characteristics in all 12 isolated Afro-descendant communities existing in the state of Mato Grosso do Sul, Central Brazil, between March 2002 and November 2003. Blood samples were collected and sera were tested for HAV antibodies (total and IgM anti-HAV) by enzyme-linked immunosorbent assay. The overall prevalence of HAV infection was 75.6 percent (95 percent CI 72.7-78.3), ranging from 55.4 to 97.3 percent, depending on the communities studied. The prevalence of anti-HAV increased significantly with age, from 13.8 percent in the age 0-5 age group to 96.6 percent in those older than 40 years. The findings point out an intermediate endemicity of HAV infection in some Afro-Brazilian isolated communities in Central Brazil. In addition, the high proportion of susceptible young subjects could be target of future HAV vaccination programs.
Full text:
Available
Index:
LILACS (Americas)
Main subject:
Hepatitis A virus
/
Hepatitis A Antibodies
/
Black People
/
Hepatitis A
Type of study:
Diagnostic study
/
Prevalence study
/
Risk factors
Limits:
Adolescent
/
Adult
/
Aged
/
Aged80
/
Child
/
Child, preschool
/
Female
/
Humans
/
Infant
/
Male
Country/Region as subject:
South America
/
Brazil
Language:
English
Journal:
Mem. Inst. Oswaldo Cruz
Journal subject:
Tropical Medicine
/
Parasitology
Year:
2007
Type:
Article
Affiliation country:
Brazil
Institution/Affiliation country:
Fundação Oswaldo Cruz/BR
/
Instituto de Patologia Tropical e Saúde Pública/BR
/
Universidade Federal de Goiás/BR
/
Universidade Federal de Mato Grosso do Sul/BR
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