First report of major histocompatibility complex class II loci from the Amazon pink river dolphin (genus Inia)
Genet. mol. res. (Online)
;
5(3): 421-431, 2006. ilus
Article
in English
| LILACS
| ID: lil-441036
ABSTRACT
We report the first major histocompatibility complex (MHC) DQB1 sequences for the two species of pink river dolphins (Inia geoffrensis and Inia boliviensis) inhabiting the Amazon and Orinoco River basins. These sequences were found to be polymorphicwithin the Inia genus and showed shared homology with cetacean DQB-1 sequences, especially, those of the Monodontidae and Phocoenidae. On the other hand, these sequences were shown to be divergent from those described for other riverine dolphin species, such as Lipotes vexillifer, the Chinese river dolphin. Two main conclusions can be drawn from our results: 1) the Mhc DQB1 sequences seem to evolve more rapidly than other nuclear sequences in cetaceans, and 2) differential positive selective pressures acting on these genes cause concomitant divergent evolutionary histories that derive phylogenetic reconstructions that could be inconsistent with widely accepted intertaxa evolutionary relationships elucidated with other molecular markers subjected to a neutraldynamics.
Full text:
Available
Index:
LILACS (Americas)
Main subject:
Genetic Variation
/
HLA-DQ Antigens
/
Evolution, Molecular
/
Dolphins
Limits:
Animals
Country/Region as subject:
South America
/
Brazil
Language:
English
Journal:
Genet. mol. res. (Online)
Journal subject:
Molecular Biology
/
Genetics
Year:
2006
Type:
Article
Affiliation country:
Colombia
/
Mexico
Institution/Affiliation country:
Pontifica Universidad Javeriana/CO
/
Universidad Autónoma de Baja California Sur/MX
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