Trombosis de la arteria renal después de suspender la terapia anticoagulante en una trasplantada renal con trombofilia: Caso Clínico / Renal artery thrombosis after withdrawal from anticoagulation therapy in a kidney transplant recipient with thrombophilia: Report of one case
Rev. méd. Chile
;
135(1): 98-102, ene. 2007.
Article
in Spanish
| LILACS
| ID: lil-443007
ABSTRACT
Kidney graft loss because arterial thrombosis is not common and is related to risk factors such as recurrent vascular hemodialysis access thrombosis, collagen-vascular disease, repeated miscarriage, diabetes mellitus and thrombophilia. Patients having this last disorder have an increased risk of repeated thrombosis in successive transplants unless they receive anticoagulation therapy. We report a 51 year-old diabetic woman who had a history of recurrent vascular hemodialysis access thrombosis (both native and prosthetic) while on dialysis and received a cadaveric donor kidney. One month after transplantation she had axillary vein thrombosis complicated with pulmonary embolism and received anticoagulants for six months. Just days after stopping the anticoagulation, she became suddenly anuric due to renal artery thrombosis and complete graft infarction. The coagulation study showed moderate hyperhomocysteinemia and a significant protein C deficiency (39 percent). Days after nephrectomy she suffered a femoral vein thrombosis and anticoagulation was prescribed for life.
Full text:
Available
Index:
LILACS (Americas)
Main subject:
Renal Artery Obstruction
/
Thrombosis
/
Kidney Transplantation
/
Thrombophilia
/
Graft Rejection
/
Anticoagulants
Type of study:
Etiology study
/
Risk factors
Limits:
Female
/
Humans
Language:
Spanish
Journal:
Rev. méd. Chile
Journal subject:
Medicine
Year:
2007
Type:
Article
Affiliation country:
Chile
Institution/Affiliation country:
Hospital Naval Almirante Nef/CL
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