Resistencia generalizada a hormonas tiroideas de carácter familiar / Familial generalized thyroid hormone resistance. Report of one case
Rev. méd. Chile
;
132(9): 1096-1099, sept. 2004. tab, graf
Article
in Spanish
| LILACS
| ID: lil-443215
ABSTRACT
Thyroid hormone resistance is a rare autosomal dominant disease associated, in more than 90% of cases, to mutations in the beta thyroid hormone receptor. We report a 23 years old male that consulted for a psychiatric condition. Clinically, the patient was euthyroid in spite of high total and free T4 and T3 concentrations, while TSH remained normal. Also, TSH showed a five fold increase under TRH stimulation. The mother and one of his brothers had the same pattern of abnormal serum thyroid hormones. We discuss the diagnostic considerations and the protocol to study this rare pathology.
Full text:
Available
Index:
LILACS (Americas)
Main subject:
Thyroid Hormones
/
Receptors, Thyroid Hormone
/
Thyroid Hormone Resistance Syndrome
Type of study:
Practice guideline
Limits:
Adult
/
Humans
/
Male
Language:
Spanish
Journal:
Rev. méd. Chile
Journal subject:
Medicine
Year:
2004
Type:
Article
Affiliation country:
Chile
Institution/Affiliation country:
Pontificia Universidad Católica de Chile/CL
Similar
MEDLINE
...
LILACS
LIS