Predição do risco de metástase do carcinoma bem diferenciado da glândula tireóide pela quantificação digital da imunoexpressão da galectina-3 nos compartimentos do tireócito maligno / Prediction of metastasis risk in well-differentiated thyroid carcinoma based on digital quantification of of galectin-3 immunoexpression in subcellular compartments of the malignant thyrocyte
São Paulo; s.n; 2006. [240] p. ilus, tab, graf.
Thesis
in Pt
| LILACS
| ID: lil-443939
Responsible library:
BR66.1
Localization: BR66.1; W4.DB8, S768p, FM-2
RESUMO
Determinar o risco da ocorrência de metástase do carcinoma bem diferenciado da glândula tireóide auxilia na escolha do tratamento adequado. Um modelo de predição individual do risco de metástase foi desenvolvido com base no estudo caso-controle de um grupo de 109 doentes operados e seguidos por mais de 5 anos. A imunomarcação da galectina-3 no nucléolo do tireócito maligno foi um fator preditivo do risco individual de metástase linfática cervical...
ABSTRACT
Determination of metastasis risk in well differentiated thyroid carcinoma allows surgeons and oncologists to offer an adequate treatment to each patient. Individual metastasis risk prediction was calculated based on a case-control study involving 109 treated patients who were followed up during at least 5 years. Nucleolar galectin-3 immuno expression in malignant thyrocytes was an individual predictive factor for cervical lymph node metastasis...
Full text:
1
Index:
LILACS
Main subject:
Thyroid Neoplasms
/
Carcinoma, Papillary
/
Adenocarcinoma, Papillary
Type of study:
Etiology_studies
/
Observational_studies
/
Prognostic_studies
/
Risk_factors_studies
Limits:
Female
/
Humans
/
Male
Language:
Pt
Year:
2006
Type:
Thesis