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Antimicrobial activity of Uncaria tomentosa against oral human pathogens
Ccahuana-Vasquez, Renzo Alberto; Santos, Silvana Soléo Ferreira dos; Koga-Ito, Cristiane Yumi; Jorge, Antonio Olavo Cardoso.
  • Ccahuana-Vasquez, Renzo Alberto; State University of Campinas. School of Dentistry. Department of Physiology Sciences. Piracicaba. BR
  • Santos, Silvana Soléo Ferreira dos; University of Taubaté. Department of Microbiology. Taubaté. BR
  • Koga-Ito, Cristiane Yumi; São Paulo State University. School of Dentistry. Department of Bioscience and Oral Diagnosis. São Paulo. BR
  • Jorge, Antonio Olavo Cardoso; University of Taubaté. Department of Microbiology. Taubaté. BR
Braz. oral res ; 21(1): 46-50, Jan.-Mar. 2007. tab
Article in English | LILACS | ID: lil-444561
ABSTRACT
Uncaria tomentosa is considered a medicinal plant used over centuries by the peruvian population as an alternative treatment for several diseases. Many microorganisms usually inhabit the human oral cavity and under certain conditions can become etiologic agents of diseases. The aim of the present study was to evaluate the antimicrobial activity of different concentrations of Uncaria tomentosa on different strains of microorganisms isolated from the human oral cavity. Micropulverized Uncaria tomentosa was tested in vitro to determine the minimum inhibitory concentration (MIC) on selected microbial strains. The tested strains were oral clinical isolates of Streptococcus mutans, Staphylococcus spp., Candida albicans, Enterobacteriaceae and Pseudomonas aeruginosa. The tested concentrations of Uncaria tomentosa ranged from 0.25-5 percent in Müeller-Hinton agar. Three percent Uncaria tomentosa inhibited 8 percent of Enterobacteriaceae isolates, 52 percent of S. mutans and 96 percent of Staphylococcus spp. The tested concentrations did not present inhibitory effect on P. aeruginosa and C. albicans. It could be concluded that micropulverized Uncaria tomentosa presented antimicrobial activity on Enterobacteriaceae, S. mutans and Staphylococcus spp. isolates.
RESUMO
Uncaria tomentosa é uma planta medicinal usada por vários séculos pela população peruana como alternativa de tratamento para diversas doenças. Muitos microrganismos que usualmente não habitam a cavidade bucal humana podem se tornar agentes etiológicos de doenças sob certas condições. O objetivo deste estudo foi avaliar a atividade antimicrobiana de diferentes concentrações de Uncaria tomentosa sobre diferentes cepas de microrganismos isolados de cavidades bucais humanas. Uncaria tomentosa micropulverizada foi testada in vitro para determinar a concentração inibitória mínima (CIM) em isolados microbianos selecionados. Cepas de Streptococcus mutans, Staphylococcus spp., Candida albicans, Enterobacteriaceae e Pseudomonas aeruginosa avaliadas foram isoladas de cavidades bucais humanas. Foram preparadas as concentrações de Uncaria tomentosa entre 0.25 e 5 por cento em ágar Müeller-Hinton. Uncaria tomentosa a 3 por cento inibiu 8 por cento de Enterobacteriaceae, 52 por cento de S. mutans e 96 por cento de Staphylococcus spp. As concentrações testadas não apresentaram efeito inibitório sobre P. aeruginosa e C. albicans. Concluiu-se que Uncaria tomentosa micropulverizada apresenta atividade antimicrobiana sobre cepas de Enterobacteriaceae, S. mutans e Staphylococcus spp.
Subject(s)
Full text: Available Index: LILACS (Americas) Main subject: Bacteria / Candida albicans / Cat's Claw / Phytotherapy / Anti-Bacterial Agents / Mouth Limits: Humans Language: English Journal: Braz. oral res Journal subject: Dentistry Year: 2007 Type: Article Affiliation country: Brazil Institution/Affiliation country: State University of Campinas/BR / São Paulo State University/BR / University of Taubaté/BR

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Full text: Available Index: LILACS (Americas) Main subject: Bacteria / Candida albicans / Cat's Claw / Phytotherapy / Anti-Bacterial Agents / Mouth Limits: Humans Language: English Journal: Braz. oral res Journal subject: Dentistry Year: 2007 Type: Article Affiliation country: Brazil Institution/Affiliation country: State University of Campinas/BR / São Paulo State University/BR / University of Taubaté/BR