A distributed computation of Interpro Pfam, PROSITE and ProDom for protein annotation
Genet. mol. res. (Online)
;
4(3): 590-598, 2005. tab, ilus
Article
in English
| LILACS
| ID: lil-444952
ABSTRACT
Interpro is a widely used tool for protein annotation in genome sequencing projects, demanding a large amount of computation and representing a huge time-consuming step. We present a strategy to execute programs using databases Pfam, PROSITE and ProDom of Interpro in a distributed environment using a Java-based messaging system. We developed a two-layer scheduling architecture of the distributed infrastructure. Then, we made experiments and analyzed the results. Our distributed system gave much better results than Interpro Pfam, PROSITE and ProDom running in a centralized platform. This approach seems to be appropriate and promising for highly demanding computational tools used for biological applications.
Full text:
Available
Index:
LILACS (Americas)
Main subject:
Database Management Systems
/
Human Genome Project
/
Computational Biology
/
Sequence Analysis, Protein
/
Databases, Protein
Limits:
Humans
Language:
English
Journal:
Genet. mol. res. (Online)
Journal subject:
Molecular Biology
/
Genetics
Year:
2005
Type:
Article
Affiliation country:
Brazil
Institution/Affiliation country:
EMBRAPA Recursos Genéticos e Biotecnologia/BR
/
Universidade de Brasília/BR
Similar
MEDLINE
...
LILACS
LIS