A framework based on Web service orchestration for bioinformatics workflow management

ABSTRACT

Bioinformatics activities are growing all over the world, with proliferation of data and tools. This brings new challenges how to understand and organize these resources and how to provide interoperability among tools to achieve a given goal. We defined and implemented a framework to help meet some of these challenges. Four issues were considered the use of Web services as a basic unit, the notion of a Semantic Web to improve interoperability at the syntactic and semantic levels, and the use of scientific workflows to coordinate services to be executed, including their interdependencies and service orchestration.