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Dispepsia funcional e depressão como fator associado / Functional dyspepsia and depression as an associated factor
Silva, Renato Azevedo da; Pinheiro, Ricardo Tavares; Silva, Ricardo Azevedo da; Horta, Bernardo Lessa; Moraes, Inácia; Faria, Augusto Duarte.
  • Silva, Renato Azevedo da; s.af
  • Pinheiro, Ricardo Tavares; s.af
  • Silva, Ricardo Azevedo da; s.af
  • Horta, Bernardo Lessa; s.af
  • Moraes, Inácia; s.af
  • Faria, Augusto Duarte; s.af
Arq. gastroenterol ; 43(4): 293-298, out.-dez. 2006. tab
Article in Portuguese | LILACS | ID: lil-445633
RESUMO
OBJETIVO: Avaliar a associação entre depressão e dispepsia funcional. PACIENTES E MÉTODOS: Estudo transversal onde foram avaliados 348 pacientes com diagnóstico de dispepsia no Ambulatório de Gastroenterologia do Hospital Universitário de Pelotas, RS, cidade de médio porte do sul do Brasil, durante o período de 1 ano (de março de 2001 a março de 2002). Após o diagnóstico de dispepsia avaliou-se a presença de depressão, tanto em pacientes com dispepsia funcional, quanto naqueles com dispepsia orgânica. Utilizou-se a análise univariada para descrição das freqüências das variáveis de interesse e da análise bivariada, com o teste qui-quadrado, para comparação entre proporções das variáveis categóricas. A técnica da regressão logística foi utilizada para estabelecer a chance dos pacientes com depressão apresentarem dispepsia funcional e para controlar o efeito das variáveis intervenientes sobre a variável de desfecho RESULTADOS: Evidenciaram maior prevalência de deprimidos entre os pacientes com dispepsia funcional (30,4 por cento) em relação àqueles com dispepsia orgânica (11,2 por cento). As mulheres apresentaram maior chance de dispepsia funcional (OR: 1,74, IC 95 por cento, 1,05-2,89) e, em relação à idade, os intervalos entre 31 e 50 anos (OR: 0,28 IC 95 por cento, 0,13-0,54) e de 51 a 60 anos (OR: 0,41, IC 95 por cento, 0,17-0,96) mostraram efeito protetor, ou seja, indivíduos nessas faixas etárias têm menor risco de apresentar dispepsia funcional. Após a análise multivariada, pacientes deprimidos apresentaram chance três vezes maior de co-morbidade com dispepsia funcional do que pacientes não-deprimidos (OR 3,13; IC 95 por cento; 1,71-5,74).
ABSTRACT
AIM: To assess the association between depression and functional dyspepsia. PATIENTS AND METHODS: Three hundred and forty eight dyspeptic patients were included in a cross-sectional study in the gastroenterology outpatient clinic of a University Hospital in southern Brazil (Pelotas, RS) within a 1-year period (from March, 2001 to March, 2002). The assessment of depression occurred after the diagnosis of dyspepsia. The presence (or not) of depression was verified in both functional and organic dyspeptic patients. In a second moment, the results were compared, an univariate analysis was used to describe the frequencies of the interest variables and a chi-square for the comparison between proportions of the categorical variables. The logistic regression technique was used to establish the odd of functional dyspeptic patients to present depression and to control the effect of other variables in the outcome variable RESULTS: Showed greater prevalence of depression among functional dyspepsia patients (30,4 percent), when compared to organic dyspepsia patients (11,2 percent). Women showed greater risk to present functional dyspepsia (OR: 1,74, IC 95 percent, 1,05-2,89) and in terms of age, the group with ages between 31 to 50 years (OR: 0,28 IC 95 percent, 0,13-0,54) and 51 to 60 years (OR: 0,41, IC 95 percent, 0,17-0,96) showed protection effect (subjects within this age groups have minor risk to present functional dyspepsia). After the multivariate analysis depressed patients showed three times greater comorbidity with functional dyspepsia when compared to non-depressed patients (OR 3, 13; IC 95 percent; 1, 71-5, 74). DISCUSSION: The adjustment for the gender, age and marital status variables confirmed the association between functional dyspepsia and depression. Results point the need to assess the presence of depression in functional dyspepsia patients and to establish specific treatment strategies for these patients.
Subject(s)
Full text: Available Index: LILACS (Americas) Main subject: Depression / Dyspepsia Type of study: Diagnostic study / Etiology study / Observational study / Prevalence study / Prognostic study / Qualitative research / Risk factors Limits: Adult / Female / Humans / Male Country/Region as subject: South America / Brazil Language: Portuguese Journal: Arq. gastroenterol Journal subject: Gastroenterology Year: 2006 Type: Article

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Full text: Available Index: LILACS (Americas) Main subject: Depression / Dyspepsia Type of study: Diagnostic study / Etiology study / Observational study / Prevalence study / Prognostic study / Qualitative research / Risk factors Limits: Adult / Female / Humans / Male Country/Region as subject: South America / Brazil Language: Portuguese Journal: Arq. gastroenterol Journal subject: Gastroenterology Year: 2006 Type: Article