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Atypical chromosome abnormalities in acute myeloid leukemia type M4
Fett-Conte, Agnes C; Estrela, Roseli Viscardi; Vendrame-Goloni, Cristina B; Carvalho-Salles, Andréa B; Ricci-Júnior, Octávio; Varella-Garcia, Marileila.
  • Fett-Conte, Agnes C; Faculdade de Medicina de São José do Rio Preto. Departamento de Biologia Molecular. São José do Rio Preto. BR
  • Estrela, Roseli Viscardi; Austa Hospital. São José do Rio Preto. BR
  • Vendrame-Goloni, Cristina B; Universidade Estadual Paulista. Letras e Ciências Exatas. Instituto de Biociências. Departamento de Biologia. São José do Rio Preto. BR
  • Carvalho-Salles, Andréa B; Faculdade de Medicina de São José do Rio Preto. Departamento de Biologia Molecular. São José do Rio Preto. BR
  • Ricci-Júnior, Octávio; Hemocentro. São José do Rio Preto. BR
  • Varella-Garcia, Marileila; University of Colorado. Comprehensive Cancer Center. Denver. US
Genet. mol. biol ; 30(1): 6-9, 2007. ilus
Article in English | LILACS | ID: lil-445675
ABSTRACT
This study reports an adult AML-M4 patient with atypical chromosomal aberrations present in all dividing bone marrow cell at diagnosis t(1;8)(p32.1;q24.2), der(9)t(9;10)(q22;?), and ins(19;9)(p13.3;q22q34) that may have originated transcripts with leukemogenic potential.
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Full text: Available Index: LILACS (Americas) Main subject: Translocation, Genetic / Leukemia, Myeloid, Acute / Chromosome Aberrations Limits: Adult / Female / Humans / Male Language: English Journal: Genet. mol. biol Journal subject: Genetics Year: 2007 Type: Article / Project document Affiliation country: Brazil / United States Institution/Affiliation country: Austa Hospital/BR / Faculdade de Medicina de São José do Rio Preto/BR / Hemocentro/BR / Universidade Estadual Paulista/BR / University of Colorado/US

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Full text: Available Index: LILACS (Americas) Main subject: Translocation, Genetic / Leukemia, Myeloid, Acute / Chromosome Aberrations Limits: Adult / Female / Humans / Male Language: English Journal: Genet. mol. biol Journal subject: Genetics Year: 2007 Type: Article / Project document Affiliation country: Brazil / United States Institution/Affiliation country: Austa Hospital/BR / Faculdade de Medicina de São José do Rio Preto/BR / Hemocentro/BR / Universidade Estadual Paulista/BR / University of Colorado/US