Wet heat exposure: a potentially reversible cause of low semen quality in infertile men
Int. braz. j. urol
;
33(1): 50-57, Jan.-Feb. 2007. tab
Article
in English
| LILACS
| ID: lil-447466
ABSTRACT
OBJECTIVE:
To evaluate the recovery of semen quality in a cohort of infertile men after known hyperthermic exposure to hot tubs, hot baths or whirlpool baths. MATERIALS ANDMETHODS:
A consecutive cohort of infertile men had a history remarkable for wet heat exposure in the forms of hot tubs, Jacuzzi or hot baths. Clinical characteristics and exposure parameters were assessed before exposure was discontinued, and semen parameters analyzed before and after discontinuation of hyperthermic exposure. A significant seminal response to withdrawal of hyperthermia was defined as > 200 percent increase in the total motile sperm count (TMC = volume x concentration x motile fraction) during follow-up after cessation of wet heat exposure.RESULTS:
Eleven infertile men (mean age 36.5 years, range 31-44) exposed to hyperthermia were evaluated pre and post-exposure. Five patients (45 percent) responded favorably to cessation of heat exposure and had a mean increase in total motile sperm counts of 491 percent. This increase was largely the result of a statistically significant increase in sperm motility from a mean of 12 percent at baseline to 34 percent post-intervention (p = 0.02). Among non-responders, a smoking history revealed a mean of 5.6 pack-years, compared to 0.11 pack-years among responders. The prevalence of varicoceles was similar in both cohorts.CONCLUSIONS:
The toxic effect of hyperthermia on semen quality may be reversible in some infertile men. We observed that the seminal response to exposure elimination varies biologically among individuals and can be profound in magnitude. Among non-responders, other risk factors that could explain a lack of response to elimination of hyperthermia should be considered.
Full text:
Available
Index:
LILACS (Americas)
Main subject:
Semen
/
Sperm Motility
/
Baths
/
Hot Temperature
/
Infertility, Male
Type of study:
Etiology study
/
Incidence study
/
Observational study
/
Risk factors
Limits:
Adult
/
Humans
/
Male
Language:
English
Journal:
Int. braz. j. urol
Journal subject:
Urology
Year:
2007
Type:
Article
Affiliation country:
United States
Institution/Affiliation country:
University of California San Francisco/US
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