Epidermodisplasia verruciforme: tratamento combinado com acitretina e interferon alfa-2a / Epidermodysplasia verruciformis: combined treatment with acitretin and interferon alpha-2a
An. bras. dermatol
;
81(6): 595-597, nov.-dez. 2006. ilus
Article
in Portuguese
| LILACS
| ID: lil-448210
RESUMO
Comunica-se o resultado do tratamento com acitretina e interferon alfa-2a em doente de 16 anos de idade com epidermodisplasia verruciforme. O diagnóstico foi realizado mediante os achados clínico-histopatológicos e pesquisa in situ positiva para papiloma vírus humano. O quadro clínico era extenso e resistente a outros tratamentos, com risco de desenvolvimento de neoplasias. Houve melhora clínica 30 dias após o início do tratamento, mantida durante os 16 meses de seguimento.
ABSTRACT
We report the result of a treatment with acitretin and alpha-2a interferon in a 16-year-old boy with epidermodysplasia verruciformis. Diagnosis was based on clinical features, histopathological examination and positivity for in situ HPV. The affection was extensive and resistant to other treatment modalities, with a high risk of development of neoplasias. Treatment with oral acitretin associated with subcutaneous recombinant interferon alpha-2a three times per week induced improvement, which was sustained for 16 months of follow-up.
Full text:
Available
Index:
LILACS (Americas)
Language:
Portuguese
Journal:
An. bras. dermatol
Journal subject:
Dermatology
Year:
2006
Type:
Article
Affiliation country:
Brazil
Institution/Affiliation country:
Hospital do Servidor Público Estadual de São Paulo/BR
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