No difference in leprosy treatment outcomes comparing 12- and 24-dose multidrug regimens: a preliminary study
Cad. saúde pública
;
23(4): 815-822, abr. 2007. graf
Article
in English
| LILACS
| ID: lil-448508
ABSTRACT
A comparative study was performed on the initial and final bacillary indexes of 213 multibacillary leprosy patients who received 12 doses (Group 1 128 patients) or 24 doses (Group 2 85 patients) of multidrug therapy (MDT/WHO) to measure the effectiveness of the two regimens. All patients were evaluated at treatment baseline, 12 months, and 24 months. The reduction in bacillary levels and mean bacillary indexes at 24 months was similar in the two groups. No statistical difference in reaction rates was observed between the two treatment regimens.
RESUMO
Foi realizado um estudo comparativo de dois grupos de pacientes definidos de acordo com o esquema terapêutico, a fim de se avaliarem os índices baciloscópicos PQT/12 doses (Grupo 1 128 pacientes) e PQT/24 doses (Grupo 2 85 pacientes). Todos os pacientes foram avaliados no início do tratamento, aos 12 meses, e novamente aos 24 meses. Ao final dos 24 meses, observou-se uma redução das médias dos índices baciloscópicos, semelhantes nos dois grupos. Não houve diferença estatística na avaliação da freqüência de quadros reacionais nos dois esquemas terapêuticos.
Full text:
Available
Index:
LILACS (Americas)
Main subject:
Leprostatic Agents
/
Leprosy
Limits:
Adolescent
/
Adult
/
Child
/
Female
/
Humans
/
Male
Language:
English
Journal:
Cad. saúde pública
Journal subject:
Public Health
/
Toxicology
Year:
2007
Type:
Article
Affiliation country:
Brazil
Institution/Affiliation country:
Fundação Oswaldo Cruz/BR
Similar
MEDLINE
...
LILACS
LIS