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Meningitis linfomatosa como sitio de recaída en la enfermedad de Hodgkin / Limphomatous meningitis as recurrence site in Hodgkin's disease
Greco, M; Valsecchi, M; Niccodemi, C; Presas, J; Corrado, C; Winkel, M.
  • Greco, M; Hospial Juan A. Fernández. Servício de Clínica Médica. Buenos Aires. AR
  • Valsecchi, M; Hospial Juan A. Fernández. Servício de Clínica Médica. Buenos Aires. AR
  • Niccodemi, C; Hospial Juan A. Fernández. Servício de Clínica Médica. Buenos Aires. AR
  • Presas, J; Hospial Juan A. Fernández. Servício de Clínica Médica. Buenos Aires. AR
  • Corrado, C; Academia Nacional de Medicina. Instituto de Investigaciones Hematológicas. Sección Onco-Hematología. Buenos Aires. AR
  • Winkel, M; Hospial Juan A. Fernández. Servício de Clínica Médica. Buenos Aires. AR
Medicina (B.Aires) ; 66(4): 332-334, 2006. ilus
Article in Spanish | LILACS | ID: lil-449012
ABSTRACT
Intracraneal manifestations of Hodgkin's Disease (HD) are extremely rare, with an estimated incidence rate of approximately 0.5%. They can be classified as 1) treatment-related leucoencephalopathy, 2) central nervous system infections, 3) paraneoplasic syndromes and 4) intracraneal lymphomas, which could be sub-classified into intraparenchymal or intradural masses. We describe a case of a 40 year-old male with mixed cellularity type HD who developed neurological manifestations as relapsed disease. Magnetic resonance imaging suggested leptomeningeal metastases and atypical cells were found in cerebrospinal fluid. The patient died from progressive disease refractory to third line chemotherapy. There are less than 50 similar cases reported in the literature. We review the clinical features and differential diagnosis of leptomeningeal metastases in Hodgkin's disease.
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Index: LILACS (Americas) Main subject: Hodgkin Disease / Meningeal Neoplasms Type of study: Diagnostic study Limits: Adult / Humans / Male Language: Spanish Journal: Medicina (B.Aires) Journal subject: Medicine Year: 2006 Type: Article Affiliation country: Argentina Institution/Affiliation country: Academia Nacional de Medicina/AR / Hospial Juan A. Fernández/AR

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Index: LILACS (Americas) Main subject: Hodgkin Disease / Meningeal Neoplasms Type of study: Diagnostic study Limits: Adult / Humans / Male Language: Spanish Journal: Medicina (B.Aires) Journal subject: Medicine Year: 2006 Type: Article Affiliation country: Argentina Institution/Affiliation country: Academia Nacional de Medicina/AR / Hospial Juan A. Fernández/AR