Intrinsic structural variation of the complex microsatellite marker MYCL1 in Finnish and Somali populations and its relevance to gastrointestinal tumors
Genet. mol. biol
;
29(4): 608-612, 2006. graf, tab
Article
in English
| LILACS
| ID: lil-450479
ABSTRACT
The structurally complex MYCL1 microsatellite marker is often used to determine microsatellite instability in colorectal cancers but the allelic variation of this marker has remained largely uncharacterized in both populations and in cancers. Our study describes the allelic distributions of MYCL1 in Finnish (n = 117) and Somali population samples (n = 61) of non-related individuals and compares this distribution with the instability pattern obtained from 61 gastrointestinal tumors.
Full text:
Available
Index:
LILACS (Americas)
Main subject:
Colorectal Neoplasms
/
Microsatellite Repeats
/
Gastrointestinal Neoplasms
Limits:
Adult
/
Aged
/
Aged80
/
Female
/
Humans
/
Male
Country/Region as subject:
Africa
/
Europa
Language:
English
Journal:
Genet. mol. biol
Journal subject:
Genetics
Year:
2006
Type:
Article
Affiliation country:
Finland
Institution/Affiliation country:
University of Helsinki/FI
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