The genetic diversity of Plasmodium vivax: a review
Mem. Inst. Oswaldo Cruz
;
102(3): 245-254, June 2007.
Article
in English
| LILACS
| ID: lil-452517
ABSTRACT
The genetic diversity of Plasmodium vivax has been investigated in several malaria-endemic areas, including the Brazilian Amazon region, where this is currently the most prevalent species causing malaria in humans. This review summarizes current views on the use of molecular markers to examine P. vivax populations, with a focus on studies performed in Brazilian research laboratories. We emphasize the importance of phylogenetic studies on this parasite and discuss the perspectives created by our increasing understanding of genetic diversity and population structure of this parasite for the development of new control strategies, including vaccines, and more effective drugs for the treatment of P. vivax malaria.
Full text:
Available
Index:
LILACS (Americas)
Main subject:
Plasmodium vivax
/
Polymorphism, Genetic
/
Genetic Variation
/
Malaria, Vivax
Limits:
Animals
/
Humans
Country/Region as subject:
South America
/
Brazil
Language:
English
Journal:
Mem. Inst. Oswaldo Cruz
Journal subject:
Tropical Medicine
/
Parasitology
Year:
2007
Type:
Article
Affiliation country:
Brazil
Institution/Affiliation country:
Faculdade de Medicina de São José do Rio Preto/BR
/
Universidade Estadual Paulista/BR
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