The use of monoclonal antibody (Rituximab) in the treatment of type II mixed cryoglobulinemia
Braz. j. infect. dis
;
11(1): 174-175, Feb. 2007.
Article
in English
| LILACS
| ID: lil-454700
ABSTRACT
Anti-CD20 monoclonal antibody has been successfully used to treat several self-immune diseases. The authors report the case of a 71 year-old female patient under the use of pegylated form of interferon á associated with ribavirin for the treatment of hepatitis C, who, after concluding the therapeutic program - negative Polymerase Chain Reaction (PCR) - developed a severe cutaneous vasculitis, receiving the diagnostic of type II mixed cryoglobulinemia. Four sessions of plasmapheresis were prescribed along the period of 11 days, with no result. The choice made was to administer anti-CD 20 monoclonal antibody (rituximab), 375 mg/m², per week, during four consecutive weeks. One could observe fast recovery from the purpura, as well as total remission of urticaria.
Full text:
Available
Index:
LILACS (Americas)
Main subject:
Cryoglobulinemia
/
Immunologic Factors
/
Antibodies, Monoclonal
Limits:
Aged
/
Female
/
Humans
Language:
English
Journal:
Braz. j. infect. dis
Journal subject:
Communicable Diseases
Year:
2007
Type:
Article
Affiliation country:
Brazil
Institution/Affiliation country:
Sírio Libanês Hospital/BR
Similar
MEDLINE
...
LILACS
LIS