Utility of the ceftazidime-imipenem antagonism test (CIAT) to detect and confirm the presence of inducible AmpC beta-lactamases among enterobacteriaceae
Braz. j. infect. dis
;
11(2): 237-239, Apr. 2007. ilus
Article
in English
| LILACS
| ID: lil-454725
ABSTRACT
Detection of AmpC beta-lactamase production by enterobacteria has been problematic. Contrary to ESBLs, no specific guidelines are available for detection and confirmation of AmpC production by clinical relevant microorganisms. Moreover, some bacterial species may produce inducible AmpC beta-lactamases that can be easily overlooked by routine susceptibility tests. We reported here a new test based on the strong inducible effect of imipenem on AmpC genes and the consequent antagonism with ceftazidime. This test is very simple and proved to be helpful in detecting AmpC-inducible enzymes among several species of clinical isolates.
Full text:
Available
Index:
LILACS (Americas)
Main subject:
Bacterial Proteins
/
Beta-Lactamases
/
Ceftazidime
/
Imipenem
/
Enterobacteriaceae
/
Anti-Bacterial Agents
Type of study:
Practice guideline
Limits:
Humans
Language:
English
Journal:
Braz. j. infect. dis
Journal subject:
Communicable Diseases
Year:
2007
Type:
Article
Affiliation country:
Brazil
Institution/Affiliation country:
Weinmann Laboratório LTDA/BR
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