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Prevalence of antibodies against hepatitis A virus among the Kuikuro and Kaiabi Indians of Xingu National Park, Brazil
Lafer, Manuel Mindlin; Moraes-Pinto, Maria Isabel de; Weckx, Lily Yin.
  • Lafer, Manuel Mindlin; s.af
  • Moraes-Pinto, Maria Isabel de; s.af
  • Weckx, Lily Yin; s.af
Rev. Inst. Med. Trop. Säo Paulo ; 49(3): 155-157, May-June 2007. tab
Article in English | LILACS | ID: lil-454762
ABSTRACT
A seroprevalence study to detect total antibodies against Hepatitis A Virus was done with 220 samples from 589 Native Indians from Xingu National Park, Brazil, in five Kaiabi and Kuikuro villages, the most populous ethnic groups. Using a commercial immunoassay kit we detected 97.7 percent positive samples (95 percent Confidence Interval 95 percent-99 percent). We noticed a precocious seroconversion, before the age of six years, when the disease is usually asymptomatic. These results are similar to those found in the literature in non-Indian population studies of the Northern, Northeastern and West Central regions of Brazil. They suggest that it is not necessary to introduce vaccination against Hepatitis A in these highly endemic populations.
RESUMO
Um estudo de soroprevalência para detectar anticorpos totais contra o Vírus da Hepatite A foi realizado com 220 amostras obtidas de 589 indivíduos de cinco aldeias indígenas das tribos Kaiabi e Kuikuro, as mais populosas do Parque Nacional do Xingu, Brasil. Utilisando um kit comercial de ensaio imunoenzimático, detectamos 97,7 por cento amostras positivas (Intervalo de Confiança de 95 por cento 95 por cento-99 por cento), com uma soroconversão precoce, antes dos seis anos de idade, quando a doença costuma ser assintomática. Estes resultados são semelhantes aos resultados encontrados na literatura em estudos com populações não-indígenas das regiões Norte, Nordeste e Centro-Oeste do Brasil, e sugere que não há necessidade de introdução de vacinação contra Hepatite A nestas populações de alta endemicidade.
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Full text: Available Index: LILACS (Americas) Main subject: Indians, South American / Hepatitis A Antibodies / Hepatitis A Type of study: Prevalence study / Risk factors Limits: Adolescent / Adult / Child / Child, preschool / Humans / Infant Country/Region as subject: South America / Brazil Language: English Journal: Rev. Inst. Med. Trop. Säo Paulo Journal subject: Tropical Medicine Year: 2007 Type: Article

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Full text: Available Index: LILACS (Americas) Main subject: Indians, South American / Hepatitis A Antibodies / Hepatitis A Type of study: Prevalence study / Risk factors Limits: Adolescent / Adult / Child / Child, preschool / Humans / Infant Country/Region as subject: South America / Brazil Language: English Journal: Rev. Inst. Med. Trop. Säo Paulo Journal subject: Tropical Medicine Year: 2007 Type: Article