First detection of a human astrovirus type 8 in a child with diarrhea in Belém, Brazil: comparison with other strains worldwide and identification of possible three lineages
Mem. Inst. Oswaldo Cruz
;
102(4): 531-534, June 2007. ilus
Article
in English
| LILACS
| ID: lil-454809
RESUMO
This study describes the genetic relationships of the first human astrovirus type-8 (HAstV-8) detected in Belém-Brazil, during a public hospital-based study. This strain was compared with other HAstV-8 strains identified elsewhere which have sequences available at GeneBank. The regions ORF1a (primers Mon348/Mon340) and ORF2 (primers Mon269/Mon270) were analyzed by nucleotide sequencing and a high similarity rate was observed among the Belém strain and other HAstV-8 strains. In ORF1a, homology values of 93-100 por cento were detected, and in ORF2 96-99 por cento. Considering the sequence variation (7 por cento) observed in ORF2 region, it was suggested that HAstV-8 strains could be divided in three different lineages.
Full text:
Available
Index:
LILACS (Americas)
Main subject:
Mamastrovirus
/
Astroviridae Infections
/
Diarrhea, Infantile
Type of study:
Diagnostic study
/
Prognostic study
Limits:
Female
/
Humans
/
Infant
Country/Region as subject:
South America
/
Brazil
Language:
English
Journal:
Mem. Inst. Oswaldo Cruz
Journal subject:
Tropical Medicine
/
Parasitology
Year:
2007
Type:
Article
Affiliation country:
Brazil
Institution/Affiliation country:
Fiocruz/BR
/
Ministério da Saúde/BR
/
Universidade Estadual do Pará/BR
/
Universidade Federal de Minas Gerais/BR
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