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Lesões anorretais em pacientes HIV positivos usuários de terapia anti-retroviral de alta efetividade / Anorrectal lesions in HIV-positive patients using highly active antiretroviral therapy
Retamozo-Palacios, Manuel; Sousa, João Batista de; Santos, João Barberino.
  • Retamozo-Palacios, Manuel; Universidade de Brasília. Núcleo de Medicina Tropical. Brasília. BR
  • Sousa, João Batista de; Hospital Universitário de Brasília. Serviço de Coloproctologia. Brasília. BR
  • Santos, João Barberino; Universidade de Brasília. Núcleo de Medicina Tropical. Brasília. BR
Rev. Soc. Bras. Med. Trop ; 40(3): 286-289, maio-jun. 2007. graf
Article in Portuguese | LILACS | ID: lil-456321
RESUMO
As lesões anorretais são comuns nos pacientes positivos para o vírus da imunodeficiência humana. A terapia antirretroviral de alta efetividade tem pouca influência na progressão das neoplasias anais. Estudou-se a prevalência das lesões anorretais em 88 pacientes HIV positivos atendidos no serviço de doenças infecto-parasitárias do Hospital Universitário de Brasília, em uso de terapia antirretroviral de alta efetividade. Dados sócio-demográficos foram coletados usando um questionário pré-elaborado e os pacientes foram submetidos a exame proctológico. Cerca de 71 por cento relataram coito anal e 30,7 por cento estavam em uso de inibidor de protease. A prevalência das lesões anorretais foi 36,4 por cento, sendo as mais freqüentes condiloma acuminado e fissura anal. O condiloma acuminado foi a lesão anorretal mais prevalente e teve associação com o uso de lopinavir/ritonavir. Sugere-se o rastreamento das lesões anorretais causadas pelo papilomavírus humano nos pacientes HIV positivos/AIDS em uso de inibidor de protease.
ABSTRACT
Anorectal lesions are common in patients with human immunodeficiency virus (HIV). Highly active anti-retroviral therapy (HAART) has little influence on the progression of anal neoplasms. The prevalence of anorectal lesions in 88 HIV-positive patients attended at the infectious diseases service of the University Hospital of Brasília who were using HAART was studied. Sociodemographic data were collected using a pre-prepared questionnaire and then the patients underwent proctological examination. Around 71 percent of the patients said they practiced anal intercourse. 30.7 percent were using a protease inhibitor. The prevalence of anorectal lesions was 36.4 percent, and condyloma acuminata and anal fissure were the most frequent of these. Condyloma acuminata was the most prevalent anorectal lesion and was strongly associated with the use of lopinavir/ritonavir. Screening for anorectal lesions caused by human papillomavirus in HIV/AIDS patients who use protease inhibitors is suggested.
Subject(s)

Full text: Available Index: LILACS (Americas) Main subject: Rectal Diseases / HIV Infections / Antiretroviral Therapy, Highly Active Type of study: Diagnostic study / Etiology study / Prevalence study / Risk factors Limits: Adult / Female / Humans / Male Country/Region as subject: South America / Brazil Language: Portuguese Journal: Rev. Soc. Bras. Med. Trop Journal subject: Tropical Medicine Year: 2007 Type: Article Affiliation country: Brazil Institution/Affiliation country: Hospital Universitário de Brasília/BR / Universidade de Brasília/BR

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Full text: Available Index: LILACS (Americas) Main subject: Rectal Diseases / HIV Infections / Antiretroviral Therapy, Highly Active Type of study: Diagnostic study / Etiology study / Prevalence study / Risk factors Limits: Adult / Female / Humans / Male Country/Region as subject: South America / Brazil Language: Portuguese Journal: Rev. Soc. Bras. Med. Trop Journal subject: Tropical Medicine Year: 2007 Type: Article Affiliation country: Brazil Institution/Affiliation country: Hospital Universitário de Brasília/BR / Universidade de Brasília/BR