Effect of a novel essential oil mouthrinse without alcohol on gingivitis: a double-blinded randomized controlled trial
J. appl. oral sci
;
15(3): 175-180, May-June 2007. graf
Article
in English
| LILACS
| ID: lil-457279
ABSTRACT
Several different plant extracts have been evaluated with respect to their antimicrobial effects against oral pathogens and for reduction of gingivitis. Given that a large number of these substances have been associated with significant side effects that contraindicate their long-term use, new compounds need to be tested. The aim of this study was to assess the short-term safety and efficacy of a Lippia sidoides ("alecrim pimenta")-based essential oil mouthrinse on gingival inflammation and bacterial plaque. Fifty-five patients were enrolled into a pilot, double-blinded, randomized, parallel-armed study. Patients were randomly assigned to undergo a 7-day treatment regimen with either the L. sidoides-based mouthrinse or 0.12 percent chlorhexidine mouthrinse. The results demonstrated decreased plaque index, gingival index and gingival bleeding index scores at 7 days, as compared to baseline. There was no statistically significance difference (p>0.05) between test and control groups for any of the clinical parameters assessed throughout the study. Adverse events were mild and transient. The findings of this study demonstrated that the L. sidoides-based mouthrinse was safe and efficacious in reducing bacterial plaque and gingival inflammation.
Full text:
Available
Index:
LILACS (Americas)
Type of study:
Controlled clinical trial
Language:
English
Journal:
J. appl. oral sci
Journal subject:
Dentistry
Year:
2007
Type:
Article
Affiliation country:
Brazil
/
United States
Institution/Affiliation country:
Federal University of Ceará/BR
/
University of Missouri/US
Similar
MEDLINE
...
LILACS
LIS