Necrosis retinal aguda en un paciente pediátrico con leucemia aguda / Acute retinal necrosis in an acute leukemia pediatric patient
Rev. chil. infectol
;
24(4): 323-326, ago. 2007. ilus
Article
in Spanish
| LILACS
| ID: lil-459598
RESUMEN
La necrosis retinal aguda (NRA) es una afección grave que amenaza la visión. Se describe en adultos, en especial aquellos profundamente inmunocompro-metidos, como consecuencia de la reactivación de virus del grupo herpes. Presentamos un paciente de 4 años de edad, con una leucemia de alto riesgo, que durante una quimioterapia intensa desarrolló una varicela con compromiso visceral, incluyendo la retina, lo que le causó ceguera unilateral. En el humor vitreo se detectó ADN de virus varicela-zoster, pese al tratamiento con aciclovir. La visión del ojo contralateral permaneció indemne.
ABSTRACT
Acute retinal necrosis (ARN) is a serious condition that can impair vision. It mostly occurs in adult patients, especially those severely immunocompromised, in association with a reactivation of a herpes virus infection. We present a 4 years old patient with high risk acute leukemia, whom during a course of intense chemotherapy acquired chickenpox with visceral involvement that affected the retina, causing unilateral blindness. Varicella-zoster virus was detected by PCR in the vitreous humor, in spite of previous acyclovir treatment. The contralateral vision remained undamaged.
Full text:
Available
Index:
LILACS (Americas)
Main subject:
Retinal Necrosis Syndrome, Acute
/
Chickenpox
/
Immunocompromised Host
/
Precursor Cell Lymphoblastic Leukemia-Lymphoma
Type of study:
Diagnostic study
Limits:
Child, preschool
/
Humans
/
Male
Language:
Spanish
Journal:
Rev. chil. infectol
Journal subject:
Communicable Diseases
Year:
2007
Type:
Article
Affiliation country:
Chile
Institution/Affiliation country:
Hospital Luis Calvo Mackenna/CL
/
Universidad de Chile/CL
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