The impact of dengue on liver function as evaluated by aminotransferase levels
Braz. j. infect. dis
;
11(4): 407-410, Aug. 2007. graf, tab
Article
in English
| LILACS
| ID: lil-460701
ABSTRACT
The objective of this study was to evaluate the impact of dengue virus infection on liver function by measuring aminotransferase in blood samples from patients serologically diagnosed by according to two MAC-ELISA protocols. Degrees of liver damage were classified according to aminotransferase levels grade A - normal enzyme levels; grade B - increased levels of at least one of the enzymes; grade C - increased, with at least one of the enzymes being at levels higher than three times the upper reference values; grade D - acute hepatitis, with aminotransferase levels at least ten times their normal values. Of the 169 serologically confirmed cases of dengue at the dengue referral center in Campos dos Goytacazes in the state of Rio de Janeiro, Brazil, 65.1 percent had abnormal aminotransferase levels 81 cases being classified as grade B, 25 as grade C and 3 as grade D. A further 34.9 percent of cases had normal enzyme levels and were classified as grade A. Liver damage is a common complication of dengue infection and aminotransferase levels are a valuable marker for monitoring these cases.
Full text:
Available
Index:
LILACS (Americas)
Main subject:
Aspartate Aminotransferases
/
Dengue
/
Alanine Transaminase
/
Liver
Type of study:
Practice guideline
Limits:
Adolescent
/
Adult
/
Aged
/
Child
/
Female
/
Humans
/
Male
Language:
English
Journal:
Braz. j. infect. dis
Journal subject:
Communicable Diseases
Year:
2007
Type:
Article
Affiliation country:
Brazil
Institution/Affiliation country:
Dengue Reference Center/BR
/
FIOCRUZ/BR
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